HEALTH COACH - Can wine protect your neurons? A study survey

HEALTH COACH -

 Can wine protect your neurons? A study survey  





 Excessive consumption of alcohol has a wide range of adverse health effects, but some previous research has indicated that moderate consumption of wine can have positive cognitive effects. A new study examines why this may be the case. A new research examines the molecular mechanism behind the neuroprotective effect of wine compounds. 
 
  
 

 Although the adverse effects of alcohol consumption are well known, some studies have indicated that a moderate consumption of red wine can delay the cognitive impairment associated with age, As well as the onset of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. 

 Moderate intake was defined in these studies as less than 250 milliliters per day. 

 A new study - published in the journal  Frontiers in Nutrition  - undertook to study the molecular mechanism behind this. 

 The researchers - led by Dr. Esteban-Fernández, of the Institute of Food Science Research in Madrid, Spain - have decided to examine the intestinal metabolites that the human body produces after consuming wine. 

 The compounds of wine prevent neuronal death, the intestinal microbiome plays a key role 

 Dr. Esteban-Fernández and the team chose these metabolites from the urine and feces of people who consume wine regularly and moderately. 

 The researchers then added these metabolites to human neurons. The researchers induced  stress  in these human cells to simulate the conditions that usually lead to neuronal death in neurodegenerative diseases. 

  The study revealed that wine - derived metabolites prevent neurons from dying under these conditions  stress . 

 Surprisingly, the results also showed that these metabolites are active at different points during the process of cell signaling which ultimately results in neuronal death. 

 According to the researchers, this means that the exact composition of the wine metabolites is crucial for this protective effect. In addition, this composition in turn depends on the composition of the intestinal microbiome, that is to say, trillions of microorganisms living within our intestines. 

 The intestinal microbiome is responsible for the treatment and destruction of wine in various metabolites, including phenolic acid and aromatic compounds - wine compounds whose neuroprotective effects have been demonstrated in this study. 

 "In other words, the differences in our intestinal microbiota lead to different metabolites. What underlies the idea that humans benefit from food in different ways, Lead author of the study. 

 A healthy diet is crucial for good brain function 

 "This individual difference is a factor that should not be overlooked to understand the health effects of certain foods. We must now advance our understanding of the effect of diet in promoting brain function Normal ", said Mr Esteban- Fernández added. 

 She also comments on the importance of a balanced diet to prevent neurodegeneration: 

 
 "It is very important to understand that certain dietary compounds are responsible for this health benefit in protecting against the onset of neurodegenerative diseases, no medication has been involved. I do not advocate replacing medication with a diet, but I want to heighten awareness [on] about how your diet helps prevent illness or reduces the risk of getting sick. It is more than possible to go to the supermarket and buy vegetables and fruits: it depends solely on individuals to maintain a balanced diet. "
 

 Although she advocates a diet rich in fruits, vegetables and saturated fats, Dr. Esteban-Fernández also warns of an excessive concern about nutrition and invites the public to discern accurate and false information about diet. 

 "Society is today full of false myths about diet, and that is the role of science and media to prevent the spread of these rumors, as well as raise awareness of people ' The importance of diet for your health, "said the author Adds. 

 Learn how a red wine compound was found to slow neuronal aging in mice.